NANODISPERSED COMPOSITE ANTIMICROBIAL MATERIALS BASED ON CALCIUM HYDROXYLAPATITE

Igor KOBASA, Galyna BILOKOPYTA, Larysa ARSENIEVA

Abstract

Some composite materials based on calcium hydroxylapatite and exhibiting antimicrobial activity have been investigated in the context of influence of the synthesis conditions on the phase composition of the materials and their antimicrobial activity against Staphylococcus aureus and Escherichia coli. It has been found that the method of synthesis involving sedimentation from the solutions of Ca(NO3)3 and (NH4)2HPO4 by ammonium hydroxide results in formation of the hydroxylapatite structures (Са10(РO4)6(ОН)2) and Ca2,993Н0,014(PO4)2 exhibiting high antimicrobial activity against the above mentioned pathogenic microbes.

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